SC 57461A
|
- $36 - $2240.7
- Product name: SC 57461A
- CAS: 423169-68-0
- MF: C20H25NO3.ClH
- MW: 363.882
- EINECS:
- MDL Number:MFCD00951253
- Synonyms:SC-57461 Hydrochloride;SC 57461A;N-methyl-N-[3-[4-(phenylmethyl)phenoxy]propyl]-β-alaninehydrochloride;SC 57461;inhibit,SC57461A,SC 57461A,Leukotriene A4,SC-57461A,Inhibitor,Aminopeptidase,orally active,LTA4 hydrolase;3-((3-(4-Benzylphenoxy)propyl)(methyl)amino)propanoic acid hydrochloride
48 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO
- 1mg
- 10
- 2mg
- 5mg
- 10mg
- 50
- 25mg
- 50mg
- 100mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 1g
- 10mM*1mLinDMSO(Solution)
- 250mg
- Manufactureraablocks
- Product numberAA00C985
- Product descriptionSC-57461A ≥98%
- Packaging1mg
- Price$36
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C985
- Product descriptionSC-57461A
- Packaging2mg
- Price$44
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C985
- Product descriptionSC-57461A
- Packaging5mg
- Price$56
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C985
- Product descriptionSC-57461A
- Packaging10mg
- Price$79
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C985
- Product descriptionSC-57461A
- Packaging25mg
- Price$138
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C985
- Product descriptionSC-57461A
- Packaging50mg
- Price$212
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C985
- Product descriptionSC-57461A
- Packaging100mg
- Price$299
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberU127714
- Product descriptionSC-57461A 98%
- Packaging100MG
- Price$415
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU127714
- Product descriptionSC-57461A 98%
- Packaging25MG
- Price$175
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3673BB
- Product description3-(Methyl(3-(4-(phenylmethyl)phenoxy)propyl)amino)propanoicacid
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3673BB
- Product description3-(Methyl(3-(4-(phenylmethyl)phenoxy)propyl)amino)propanoicacid
- Packaging10mg
- Price$286
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0010337
- Product descriptionN-METHYL-N-[3-[4-(PHENYLMETHYL)PHENOXY]PROPYL]-BETA-ALANINE HYDROCHLORIDE 95.00%
- Packaging10MG
- Price$785.4
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0010337
- Product descriptionN-METHYL-N-[3-[4-(PHENYLMETHYL)PHENOXY]PROPYL]-BETA-ALANINE HYDROCHLORIDE 95.00%
- Packaging100MG
- Price$2240.7
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4408
- Product descriptionSC 57461A
- Packaging50mg
- Price$1078
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4408
- Product descriptionSC 57461A
- Packaging25mg
- Price$525
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4408
- Product descriptionSC 57461A
- Packaging10mg
- Price$235
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00C985 | SC-57461A ≥98% | 1mg | $36 | 2026-05-28 | Buy |
| aablocks | AA00C985 | SC-57461A | 2mg | $44 | 2026-05-28 | Buy |
| aablocks | AA00C985 | SC-57461A | 5mg | $56 | 2026-05-28 | Buy |
| aablocks | AA00C985 | SC-57461A | 10mg | $79 | 2026-05-28 | Buy |
| aablocks | AA00C985 | SC-57461A | 25mg | $138 | 2026-05-28 | Buy |
| aablocks | AA00C985 | SC-57461A | 50mg | $212 | 2026-05-28 | Buy |
| aablocks | AA00C985 | SC-57461A | 100mg | $299 | 2026-05-28 | Buy |
| ACHEMBLOCK | U127714 | SC-57461A 98% | 100MG | $415 | 2026-05-27 | Buy |
| ACHEMBLOCK | U127714 | SC-57461A 98% | 25MG | $175 | 2026-05-27 | Buy |
| AK Scientific | 3673BB | 3-(Methyl(3-(4-(phenylmethyl)phenoxy)propyl)amino)propanoicacid | 1mg | $133 | 2021-12-16 | Buy |
| AK Scientific | 3673BB | 3-(Methyl(3-(4-(phenylmethyl)phenoxy)propyl)amino)propanoicacid | 10mg | $286 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010337 | N-METHYL-N-[3-[4-(PHENYLMETHYL)PHENOXY]PROPYL]-BETA-ALANINE HYDROCHLORIDE 95.00% | 10MG | $785.4 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010337 | N-METHYL-N-[3-[4-(PHENYLMETHYL)PHENOXY]PROPYL]-BETA-ALANINE HYDROCHLORIDE 95.00% | 100MG | $2240.7 | 2021-12-16 | Buy |
| ApexBio Technology | A4408 | SC 57461A | 50mg | $1078 | 2026-05-06 | Buy |
| ApexBio Technology | A4408 | SC 57461A | 25mg | $525 | 2026-05-06 | Buy |
| ApexBio Technology | A4408 | SC 57461A | 10mg | $235 | 2026-05-06 | Buy |
Properties
Melting point :163-165°C
storage temp. :Desiccate at +4°C
solubility :DMSO: >5mg/mL
form :powder
color :white to off-white
InChI :1S/C20H25NO3.ClH/c1-21(14-12-20(22)23)13-5-15-24-19-10-8-18(9-11-19)16-17-6-3-2-4-7-17;/h2-4,6-11H,5,12-16H2,1H3,(H,22,23);1H
InChIKey :SBBJJLDNKNNWFJ-UHFFFAOYSA-N
SMILES :Cl.CN(CCCOc1ccc(Cc2ccccc2)cc1)CCC(O)=O
storage temp. :Desiccate at +4°C
solubility :DMSO: >5mg/mL
form :powder
color :white to off-white
InChI :1S/C20H25NO3.ClH/c1-21(14-12-20(22)23)13-5-15-24-19-10-8-18(9-11-19)16-17-6-3-2-4-7-17;/h2-4,6-11H,5,12-16H2,1H3,(H,22,23);1H
InChIKey :SBBJJLDNKNNWFJ-UHFFFAOYSA-N
SMILES :Cl.CN(CCCOc1ccc(Cc2ccccc2)cc1)CCC(O)=O
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Leukotriene A4 (LTA4) hydrolase/aminopeptidase is a bifunctional zinc metalloenzyme that both catalyzes the synthesis of LTB4 from LTA4 and cleaves the chemotactic peptide Pro-Gly-Pro. SC-57461A is a potent, orally active inhibitor of LTA4 hydrolase that blocks ionophore-stimulated LTB4 synthesis in whole blood (IC50 = 49 nM). It blocks both the hydrolase and aminopeptidase activity in vitro. SC-57461A is without effect against other enzymes of the arachidonic acid cascade, including 5-lipoxygenase, LTC4 synthase, COX-1, and COX-2. In a rat model of ionophore-induced peritoneal eicosanoid production, SC-57461A inhibits LTB4 biosynthesis without affecting LTC4 or 6-keto prostaglandin F1α production . Oral or topical pretreatment with SC-57461A before challenge with arachidonic acid blocks ear edema in mice.Related product price
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