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ChemicalBook >> CAS DataBase List >> SKI II

SKI II

$32 - $2250
Product name: SKI II
CAS: 312636-16-1
MF: C15H11ClN2OS
MW: 302.78
EINECS:
MDL Number:MFCD00733553
Synonyms:SKIII(SphK-I2), >98%;SKI II - SKI 2;SPHINGOSINE KINASE INHIBITOR;SPHINGOSINE KINASE INHIBITOR 2;SKI II (SPHK-I2);SPHK-I2;SKI II (SPHINGOSINE KINASE INHIBITOR);CS-1145;Sphingosine Kinase Inhibitor;Sphingosine Kinase Inhibitor 2;SKI II (SphK-I2);SphK-I2

Price43 Properties Safety Information Description

43 prices

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Brand

AK Scientific
Ambeed
American Custom Chemicals Corporation
ApexBio Technology
Axon Medchem
Biosynth Carbosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
Medical Isotopes, Inc.
Sigma-Aldrich
TRC
Usbiological

Package

10mg
25mg
5mg
10mM(in 1mL DMSO)
50mg
100mg
200mg
250mg
1g

ManufacturerAK Scientific
Product numberAMTA096
Product descriptionSphingosineKinaseInhibitor2
Packaging5mg
Price$32
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number2038AH
Product description4-[[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]amino]phenol
Packaging250mg
Price$338
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA122860
Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
Packaging5mg
Price$40
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA122860
Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
Packaging10mg
Price$52
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA122860
Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
Packaging25mg
Price$73
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA122860
Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
Packaging50mg
Price$95
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA122860
Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
Packaging100mg
Price$124
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA122860
Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
Packaging250mg
Price$206
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA122860
Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
Packaging1g
Price$504
Updated2021-12-16
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ManufacturerAmerican Custom Chemicals Corporation
Product numberKIN0001270
Product descriptionSKI II 95.00%
Packaging5MG
Price$450
Updated2021-12-16
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ManufacturerAmerican Custom Chemicals Corporation
Product numberKIN0001270
Product descriptionSKI II 95.00%
Packaging10MG
Price$617.3
Updated2021-12-16
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ManufacturerAmerican Custom Chemicals Corporation
Product numberKIN0001270
Product descriptionSKI II 95.00%
Packaging50MG
Price$846.5
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB2226
Product descriptionSKI II
Packaging10mM(in 1mL DMSO)
Price$60
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB2226
Product descriptionSKI II
Packaging25mg
Price$103
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberB2226
Product descriptionSKI II
Packaging100mg
Price$329
Updated2021-12-16
Buy

ManufacturerAxon Medchem
Product numberAxon2782
Product descriptionSKIII-SKI2 99%
Packaging10mg
Price$93.5
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AK Scientific	AMTA096	SphingosineKinaseInhibitor2	5mg	$32	2021-12-16	Buy
AK Scientific	2038AH	4-[[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]amino]phenol	250mg	$338	2021-12-16	Buy
Ambeed	A122860	4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%	5mg	$40	2021-12-16	Buy
Ambeed	A122860	4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%	10mg	$52	2021-12-16	Buy
Ambeed	A122860	4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%	25mg	$73	2021-12-16	Buy
Ambeed	A122860	4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%	50mg	$95	2021-12-16	Buy
Ambeed	A122860	4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%	100mg	$124	2021-12-16	Buy
Ambeed	A122860	4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%	250mg	$206	2021-12-16	Buy
Ambeed	A122860	4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%	1g	$504	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0001270	SKI II 95.00%	5MG	$450	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0001270	SKI II 95.00%	10MG	$617.3	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0001270	SKI II 95.00%	50MG	$846.5	2021-12-16	Buy
ApexBio Technology	B2226	SKI II	10mM(in 1mL DMSO)	$60	2021-12-16	Buy
ApexBio Technology	B2226	SKI II	25mg	$103	2021-12-16	Buy
ApexBio Technology	B2226	SKI II	100mg	$329	2021-12-16	Buy
Axon Medchem	Axon2782	SKIII-SKI2 99%	10mg	$93.5	2021-12-16	Buy

Next Last

Properties

Boiling point :507.1±60.0 °C(Predicted)
Density :1.415±0.06 g/cm3(Predicted)
RTECS :SK5900000
storage temp. :2-8°C
solubility :DMSO: ≥20 mg/mL
form :solid
pka :10.17±0.26(Predicted)
color :off-white
Sensitive :Air & Light Sensitive
CAS DataBase Reference :312636-16-1

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning		P264, P270, P301+P312, P330, P501

Precautionary statements:

P280	Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SKI II is a selective non-lipid inhibitor of SphK(sphingosine kinase) (IC₅₀ = 0.5 M); does not act at ATP-binding site. SKI II displays no inhibition of ERK2, PI 3-kinase, or PKCα at concentrations up to 60 μM. Reduces levels of sphingosine-1-phosphate in MDA-MB-231 breast cancer cells. SKI II induces apoptosis and inhibits prpliferation in several other tumor cell lines in vitro (IC₅₀ = 0.9-4.6 μM).

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Suppliers and manufacturers

TargetMol Chemicals Inc.

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SKI II CAS:312636-16-1

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SKI II

Properties

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Description

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