STX140
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- $73 - $2895.5
- Product name: STX140
- CAS: 401600-86-0
- MF: C19H28N2O7S2
- MW: 460.56
- EINECS:
- MDL Number:
- Synonyms:STX140;Estra-1,3,5(10)-triene-3,17-diol, 2-methoxy-, disulfamate, (17β)-;2-methoxy-estra-1,3,5(10)-triene-3,17β-diol, disulfamate;(9Beta,13α,14Beta,17α)-2-Methoxyestra-1,3,5(10)-triene-3,17-diyl disulfamate
20 prices
Selected condition：
Brand
- aablocks
- Biosynth
- Cayman Chemical
- ChemScene
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- Manufactureraablocks
- Product numberAA01LIWD
- Product descriptionSTX140 ≥98%
- Packaging1mg
- Price$81
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01LIWD
- Product descriptionSTX140 ≥98%
- Packaging5mg
- Price$357
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01LIWD
- Product descriptionSTX140 ≥98%
- Packaging10mg
- Price$633
- Updated2026-05-30
- Buy
- ManufacturerBiosynth
- Product numberBRA60086
- Product description(9Beta,13α,14Beta,17α)-2-Methoxyestra-1,3,5(10)-triene-3,17-diyl disulfamate
- Packaging25mg
- Price$1809.75
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberBRA60086
- Product description(9Beta,13α,14Beta,17α)-2-Methoxyestra-1,3,5(10)-triene-3,17-diyl disulfamate
- Packaging50mg
- Price$2895.5
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberBRA60086
- Product description(9Beta,13α,14Beta,17α)-2-Methoxyestra-1,3,5(10)-triene-3,17-diyl disulfamate
- Packaging10mg
- Price$965.2
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberBRA60086
- Product description(9Beta,13α,14Beta,17α)-2-Methoxyestra-1,3,5(10)-triene-3,17-diyl disulfamate
- Packaging5mg
- Price$603.25
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberBRA60086
- Product description(9Beta,13α,14Beta,17α)-2-Methoxyestra-1,3,5(10)-triene-3,17-diyl disulfamate
- Packaging1mg
- Price$250
- Updated2026-06-04
- Buy
- ManufacturerCayman Chemical
- Product number27863
- Product descriptionSTX140
- Packaging10mg
- Price$575
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27863
- Product descriptionSTX140 ≥98%
- Packaging10mg
- Price$633
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number27863
- Product descriptionSTX140
- Packaging5mg
- Price$324
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27863
- Product descriptionSTX140 ≥98%
- Packaging5mg
- Price$357
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number27863
- Product descriptionSTX140
- Packaging1mg
- Price$73
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27863
- Product descriptionSTX140 ≥98%
- Packaging1mg
- Price$81
- Updated2026-04-30
- Buy
- ManufacturerChemScene
- Product numberCS-0113469
- Product descriptionSTX140
- Packaging1mg
- Price$286
- Updated2026-06-04
- Buy
- ManufacturerChemScene
- Product numberCS-0113469
- Product descriptionSTX140
- Packaging1mg
- Price$286
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01LIWD | STX140 ≥98% | 1mg | $81 | 2026-05-30 | Buy |
| aablocks | AA01LIWD | STX140 ≥98% | 5mg | $357 | 2026-05-30 | Buy |
| aablocks | AA01LIWD | STX140 ≥98% | 10mg | $633 | 2026-05-30 | Buy |
| Biosynth | BRA60086 | (9Beta,13α,14Beta,17α)-2-Methoxyestra-1,3,5(10)-triene-3,17-diyl disulfamate | 25mg | $1809.75 | 2026-06-04 | Buy |
| Biosynth | BRA60086 | (9Beta,13α,14Beta,17α)-2-Methoxyestra-1,3,5(10)-triene-3,17-diyl disulfamate | 50mg | $2895.5 | 2026-06-04 | Buy |
| Biosynth | BRA60086 | (9Beta,13α,14Beta,17α)-2-Methoxyestra-1,3,5(10)-triene-3,17-diyl disulfamate | 10mg | $965.2 | 2026-06-04 | Buy |
| Biosynth | BRA60086 | (9Beta,13α,14Beta,17α)-2-Methoxyestra-1,3,5(10)-triene-3,17-diyl disulfamate | 5mg | $603.25 | 2026-06-04 | Buy |
| Biosynth | BRA60086 | (9Beta,13α,14Beta,17α)-2-Methoxyestra-1,3,5(10)-triene-3,17-diyl disulfamate | 1mg | $250 | 2026-06-04 | Buy |
| Cayman Chemical | 27863 | STX140 | 10mg | $575 | 2024-03-01 | Buy |
| Cayman Chemical | 27863 | STX140 ≥98% | 10mg | $633 | 2026-04-30 | Buy |
| Cayman Chemical | 27863 | STX140 | 5mg | $324 | 2024-03-01 | Buy |
| Cayman Chemical | 27863 | STX140 ≥98% | 5mg | $357 | 2026-04-30 | Buy |
| Cayman Chemical | 27863 | STX140 | 1mg | $73 | 2024-03-01 | Buy |
| Cayman Chemical | 27863 | STX140 ≥98% | 1mg | $81 | 2026-04-30 | Buy |
| ChemScene | CS-0113469 | STX140 | 1mg | $286 | 2026-06-04 | Buy |
| ChemScene | CS-0113469 | STX140 | 1mg | $286 | 2026-06-04 | Buy |
Properties
Boiling point :644.8±65.0 °C(Predicted)
Density :1.47±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:7): 0.1 mg/ml; DMSO: 25 mg/ml; Ethanol: 14 mg/ml
form :A crystalline solid
pka :8.81±0.70(Predicted)
Density :1.47±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:7): 0.1 mg/ml; DMSO: 25 mg/ml; Ethanol: 14 mg/ml
form :A crystalline solid
pka :8.81±0.70(Predicted)
Safety Information
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Description
STX140 is an estrogen sulfamate with anticancer activities. It inhibits steroid sulfatase with IC50 values of 39 and 0.5 nM in placental microsomes and MCF-7 cancer cells, respectively. STX140 also binds to carbonic anhydrase IX and II (Kis = 70 and 270 nM, respectively). It inhibits bovine brain tubulin assembly in a cell-free assay (IC50 = 2.2 μM) and tubule formation in human umbilical vein epithelial cells (HUVECs) when used at concentrations of 50 and 100 nM. STX140 inhibits proliferation of LNCaP, PC3, and MDA-MB-231 cancer cells, as well as wild-type A2780 cancer cells and adriamycin- and cisplatin-resistant A2780 cancer cells (IC50s = 530, 400, 618, 330, 870, and 380 nM, respectively). It reduces angiogenesis in a Matrigel™ plug assay in mice and tumor growth in MCF-7 and MDA-MB-231 mouse xenograft models when used at a dose of 20 mg/kg.Related product price
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