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ChemicalBook >> CAS DataBase List >> Seneciphylline

Seneciphylline

Seneciphylline price.
  • $37 - $3165
  • Product name: Seneciphylline
  • CAS: 480-81-9
  • MF: C18H23NO5
  • MW: 333.38
  • EINECS:
  • MDL Number:MFCD00221722
  • Synonyms:ALPHA-LONGILOBINE;(15cis)-12-Hydroxy-13,19-didehydrosenecionan-11,16-dione;13,19-didehydro-12-hydroxysenecionan-11,16-dione ;16-dione,13,19-didehydro-12-hydroxy-senecionan-1 ;16-dione,13,19-didehydro-12-hydroxy-senecionin-1 ;NSC 30622;oxy-6-methyl-5-methylene(1,6)dioxacyclodode/// ;Pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene(1,6)dioxacyclododecino(2,3,4-gh)-
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  • aablocks
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  • American Custom Chemicals Corporation
  • Arctom
  • Cayman Chemical
  • ChemScene
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  • Sigma-Aldrich
  • TRC
Package
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 2.5mg
  • 1mg
  • 10mM*1mLinDMSO(Solution)
  • 5mg
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  • Manufactureraablocks
  • Product numberAA00I8O6
  • Product description(3Z,6R,14aR,14bR)-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione ≥98%
  • Packaging1mg
  • Price$41
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00I8O6
  • Product description(3Z,6R,14aR,14bR)-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione
  • Packaging5mg
  • Price$135
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00I8O6
  • Product description(3Z,6R,14aR,14bR)-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione
  • Packaging10mg
  • Price$203
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00I8O6
  • Product description(3Z,6R,14aR,14bR)-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione
  • Packaging25mg
  • Price$332
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00I8O6
  • Product description(3Z,6R,14aR,14bR)-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione
  • Packaging50mg
  • Price$478
  • Updated2026-05-29
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  • ManufacturerACHEMBLOCK
  • Product numberV155926
  • Product descriptionSeneciphylline 98%
  • Packaging50MG
  • Price$685
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberV155926
  • Product descriptionSeneciphylline 98%
  • Packaging5MG
  • Price$170
  • Updated2026-05-27
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0032134
  • Product descriptionSENECIPHYLLIN 95.00%
  • Packaging5MG
  • Price$504.03
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAB2609
  • Product descriptionSeneciphylline 98%(HPLC)
  • Packaging500mg
  • Price$1966
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberAB2609
  • Product descriptionSeneciphylline 98%(HPLC)
  • Packaging1000mg
  • Price$3165
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-N1282
  • Product descriptionSeneciphylline 99.93%
  • Packaging1mg
  • Price$84
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberAB2609
  • Product descriptionSeneciphylline 98%(HPLC)
  • Packaging20mg
  • Price$338
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-N1282
  • Product descriptionSeneciphylline 99.93%
  • Packaging10mg
  • Price$392
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberCFN98747
  • Product descriptionSeneciphylline ≥98%
  • Packaging5mg
  • Price$238
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberHY-N1282
  • Product descriptionSeneciphylline 99.93%
  • Packaging5mg
  • Price$245
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-N1282
  • Product descriptionSeneciphylline 99.93%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$269
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00I8O6 (3Z,6R,14aR,14bR)-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione ≥98% 1mg $41 2026-05-29 Buy
aablocks AA00I8O6 (3Z,6R,14aR,14bR)-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione 5mg $135 2026-05-29 Buy
aablocks AA00I8O6 (3Z,6R,14aR,14bR)-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione 10mg $203 2026-05-29 Buy
aablocks AA00I8O6 (3Z,6R,14aR,14bR)-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione 25mg $332 2026-05-29 Buy
aablocks AA00I8O6 (3Z,6R,14aR,14bR)-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione 50mg $478 2026-05-29 Buy
ACHEMBLOCK V155926 Seneciphylline 98% 50MG $685 2026-05-27 Buy
ACHEMBLOCK V155926 Seneciphylline 98% 5MG $170 2026-05-27 Buy
American Custom Chemicals Corporation CHM0032134 SENECIPHYLLIN 95.00% 5MG $504.03 2021-12-16 Buy
Arctom AB2609 Seneciphylline 98%(HPLC) 500mg $1966 2026-05-26 Buy
Arctom AB2609 Seneciphylline 98%(HPLC) 1000mg $3165 2026-05-26 Buy
Arctom HY-N1282 Seneciphylline 99.93% 1mg $84 2026-05-26 Buy
Arctom AB2609 Seneciphylline 98%(HPLC) 20mg $338 2026-05-26 Buy
Arctom HY-N1282 Seneciphylline 99.93% 10mg $392 2026-05-26 Buy
Arctom CFN98747 Seneciphylline ≥98% 5mg $238 2021-12-16 Buy
Arctom HY-N1282 Seneciphylline 99.93% 5mg $245 2026-05-26 Buy
Arctom HY-N1282 Seneciphylline 99.93% 10mM*1mLinDMSO(Solid+Solvent) $269 2026-05-26 Buy

Properties

Melting point :217°C
alpha :D -128° (chloroform)
Boiling point :470.34°C (rough estimate)
Density :1.2467 (rough estimate)
refractive index :1.5740 (estimate)
storage temp. :-20°C
solubility :DMF: 5 mg/ml; DMSO: 2 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 0.1 mg/ml
form :Solid
pka :12.43±0.20(Predicted)
color :White to off-white
Stability :Stable, but reacts with oxygen in the air. Incompatible with alkali, oxidizing agents. Store under inert gas.
LogP :0.810 (est)
CAS DataBase Reference :480-81-9
IARC :3 (Vol. 10, Sup 7) 1987
EPA Substance Registry System :Seneciphylline (480-81-9)

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Seneciphylline, a pyrrolizidine alkaloid, one of the main components of Chinese medicine herb Tusanqi, which is a reason of the hepatic sinusoidal obstruction syndrome (HSOS). In addition, experiments on rats have shown that seneciphylline had adverse effects on the development and organic morphodifferentiation of embryos, thus the pregnant people exposed to Hebra may get potential risk on the fetus.

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