WWL113
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- $41 - $2072
- Product name: WWL113
- CAS: 947669-86-5
- MF: C29H26N2O4
- MW: 466.52774
- EINECS:
- MDL Number:MFCD28160857
- Synonyms:WWL113;AKIIPHDGVCFVCC-UHFFFAOYSA-N;ethyl 4-[4-[methyl-[(3-pyridin-4-ylphenyl)methyl]carbamoyl]oxyphenyl]benzoate;4'-[[[Methyl[[3-(4-pyridinyl)phenyl]methyl]amino]carbonyl]oxy]-[1,1'-biphenyl]-4-carboxylic acid ethyl ester;WWL-113,WWL113;[1,1'-Biphenyl]-4-carboxylic acid, 4'-[[[methyl[[3-(4-pyridinyl)phenyl]methyl]amino]carbonyl]oxy]-, ethyl ester
33 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solution)
- 1mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 5 mg
- 25 mg
- Manufactureraablocks
- Product numberAA01DNQD
- Product descriptionWWL113 ≥98%
- Packaging1mg
- Price$41
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DNQD
- Product descriptionWWL113 ≥98%
- Packaging5mg
- Price$99
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DNQD
- Product descriptionWWL113 ≥98%
- Packaging10mg
- Price$178
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DNQD
- Product descriptionWWL113
- Packaging25mg
- Price$331
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DNQD
- Product descriptionWWL113
- Packaging50mg
- Price$533
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DNQD
- Product descriptionWWL113
- Packaging100mg
- Price$889
- Updated2026-05-29
- Buy
- ManufacturerAK Scientific
- Product numberSYN5248
- Product descriptionWWL113
- Packaging100mg
- Price$925
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5248
- Product descriptionWWL113
- Packaging50mg
- Price$560
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-110148
- Product descriptionWWL113 99.72%
- Packaging100mg
- Price$770
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-110148
- Product descriptionWWL113 99.72%
- Packaging50mg
- Price$485
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-110148
- Product descriptionWWL113 99.72%
- Packaging25mg
- Price$285
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-110148
- Product descriptionWWL113 99.72%
- Packaging10mg
- Price$133
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-110148
- Product descriptionWWL113 99.72%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$75
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-110148
- Product descriptionWWL113 99.72%
- Packaging5mg
- Price$76
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-110148
- Product descriptionWWL113 99.72%
- Packaging10mM*1mLinDMSO(Solution)
- Price$78
- Updated2026-05-26
- Buy
- ManufacturerBiosynth
- Product numberXMB66986
- Product descriptionWWL113
- Packaging25mg
- Price$931.25
- Updated2026-06-05
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01DNQD | WWL113 ≥98% | 1mg | $41 | 2026-05-29 | Buy |
| aablocks | AA01DNQD | WWL113 ≥98% | 5mg | $99 | 2026-05-29 | Buy |
| aablocks | AA01DNQD | WWL113 ≥98% | 10mg | $178 | 2026-05-29 | Buy |
| aablocks | AA01DNQD | WWL113 | 25mg | $331 | 2026-05-29 | Buy |
| aablocks | AA01DNQD | WWL113 | 50mg | $533 | 2026-05-29 | Buy |
| aablocks | AA01DNQD | WWL113 | 100mg | $889 | 2026-05-29 | Buy |
| AK Scientific | SYN5248 | WWL113 | 100mg | $925 | 2021-12-16 | Buy |
| AK Scientific | SYN5248 | WWL113 | 50mg | $560 | 2021-12-16 | Buy |
| Arctom | HY-110148 | WWL113 99.72% | 100mg | $770 | 2026-05-26 | Buy |
| Arctom | HY-110148 | WWL113 99.72% | 50mg | $485 | 2026-05-26 | Buy |
| Arctom | HY-110148 | WWL113 99.72% | 25mg | $285 | 2026-05-26 | Buy |
| Arctom | HY-110148 | WWL113 99.72% | 10mg | $133 | 2026-05-26 | Buy |
| Arctom | HY-110148 | WWL113 99.72% | 10mM*1mLinDMSO(Solid+Solvent) | $75 | 2026-05-26 | Buy |
| Arctom | HY-110148 | WWL113 99.72% | 5mg | $76 | 2026-05-26 | Buy |
| Arctom | HY-110148 | WWL113 99.72% | 10mM*1mLinDMSO(Solution) | $78 | 2026-05-26 | Buy |
| Biosynth | XMB66986 | WWL113 | 25mg | $931.25 | 2026-06-05 | Buy |
Properties
Boiling point :630.9±55.0 °C(Predicted)
Density :1+-.0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 25 mg/ml; DMF:PBS(pH7.2) (1:2): 0.3 mg/ml; DMSO: 15 mg/ml; Ethanol: 0.1 mg/ml
form :A crystalline solid
pka :5.18±0.26(Predicted)
color :White to off-white
InChI :1S/C29H26N2O4/c1-3-34-28(32)25-9-7-22(8-10-25)23-11-13-27(14-12-23)35-29(33)31(2)20-21-5-4-6-26(19-21)24-15-17-30-18-16-24/h4-19H,3,20H2,1-2H3
InChIKey :AKIIPHDGVCFVCC-UHFFFAOYSA-N
SMILES :CCOC(C(C=C1)=CC=C1C(C=C2)=CC=C2OC(N(C)CC3=CC(C4=CC=NC=C4)=CC=C3)=O)=O
Density :1+-.0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 25 mg/ml; DMF:PBS(pH7.2) (1:2): 0.3 mg/ml; DMSO: 15 mg/ml; Ethanol: 0.1 mg/ml
form :A crystalline solid
pka :5.18±0.26(Predicted)
color :White to off-white
InChI :1S/C29H26N2O4/c1-3-34-28(32)25-9-7-22(8-10-25)23-11-13-27(14-12-23)35-29(33)31(2)20-21-5-4-6-26(19-21)24-15-17-30-18-16-24/h4-19H,3,20H2,1-2H3
InChIKey :AKIIPHDGVCFVCC-UHFFFAOYSA-N
SMILES :CCOC(C(C=C1)=CC=C1C(C=C2)=CC=C2OC(N(C)CC3=CC(C4=CC=NC=C4)=CC=C3)=O)=O
Safety Information
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Description
Mouse carboxylesterase 3 (Ces3, also named Ces 1d) mediates triglyceride hydrolysis in white adipose tissue, liberating free fatty acids into circulation. Although important for basal lipolysis, Ces3 expression can be induced by xenobiotics. Ces3 activity is significantly elevated during adipocyte differentiation. WWL113 is a selective inhibitor of Ces3 and the structurally related Ces 1f (IC50 = ~0.1 μM) without significantly affecting several related enzymes. It significantly reduces basal lipolysis in adipocytes. More interestingly, WWL113 corrects multiple features of metabolic syndrome in obese-diabetic db/db mice, including changes in weight gain, glucose tolerance, and levels of nonesterified free fatty acids, triglycerides, total cholesterol, and fasted glucose. It has similar effects in mice with diet-induced obesity. WWL113 also inhibits the human ortholog of mouse Ces3, hCES1 (IC50 = ~50 nM), which has a similar tissue expression pattern to Ces3.Suppliers and manufacturers
TargetMol Chemicals Inc.
Aladdin Scientific
Amadis Chemical Company Limited
Shanghai EFE Biological Technology Co., Ltd.
BOC Sciences
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
ShangHai ChuanQian Chemcial Technique Centre
Beijing Jin Ming Biotechnology Co., Ltd.
TargetMol Chemicals Inc.
