YW1128
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- $69 - $4766.8
- Product name: YW1128
- CAS: 2131223-64-6
- MF: C20H17N5O
- MW: 343.38
- EINECS:
- MDL Number:
- Synonyms:3-triazole-4-carboxamide;5-methyl-1-(2-methylphenyl)-N-2-quinolinyl-1H-1;5-METHYL-1-(2-METHYLPHENYL)-N-2-QUINOLINYL-1H-1;2;3-TRIAZOLE-4-CARBOXAMIDE;YW1128;1H-1,2,3-Triazole-4-carboxamide, 5-methyl-1-(2-methylphenyl)-N-2-quinolinyl-;YW1128,YW-1128
25 prices
Selected condition:
Brand
- aablocks
- AK Scientific
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- DC Chemicals
Package
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 1mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 5mg
- 10mg
- 10mM*1mLinDMSO(Solution)
- Manufactureraablocks
- Product numberAA01LJ14
- Product descriptionYW1128 ≥98%
- Packaging1mg
- Price$69
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01LJ14
- Product descriptionYW1128 ≥98%
- Packaging5mg
- Price$313
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01LJ14
- Product descriptionYW1128 ≥98%
- Packaging10mg
- Price$591
- Updated2026-05-30
- Buy
- ManufacturerAK Scientific
- Product number0851EN
- Product description5-Methyl-1-(2-methylphenyl)-N-quinolin-2-yltriazole-4-carboxamide
- Packaging1mg
- Price$166
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-133180
- Product descriptionYW1128 99.38%
- Packaging5mg
- Price$195
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-133180
- Product descriptionYW1128 99.38%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$204
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-133180
- Product descriptionYW1128 99.38%
- Packaging10mM*1mLinDMSO(Solution)
- Price$214
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-133180
- Product descriptionYW1128 99.38%
- Packaging10mg
- Price$314
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-133180
- Product descriptionYW1128 99.38%
- Packaging25mg
- Price$627
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-133180
- Product descriptionYW1128 99.38%
- Packaging50mg
- Price$1003
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-133180
- Product descriptionYW1128 99.38%
- Packaging100mg
- Price$1604
- Updated2026-05-26
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611984
- Product descriptionYW1128 >98%
- Packaging250mg
- Price$2395.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611984
- Product descriptionYW1128 >98%
- Packaging1g
- Price$4766.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611984
- Product descriptionYW1128 >98%
- Packaging100mg
- Price$1431.4
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number27450
- Product descriptionYW1128 ≥98%
- Packaging1mg
- Price$69
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number27450
- Product descriptionYW1128 ≥98%
- Packaging5mg
- Price$313
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01LJ14 | YW1128 ≥98% | 1mg | $69 | 2026-05-30 | Buy |
| aablocks | AA01LJ14 | YW1128 ≥98% | 5mg | $313 | 2026-05-30 | Buy |
| aablocks | AA01LJ14 | YW1128 ≥98% | 10mg | $591 | 2026-05-30 | Buy |
| AK Scientific | 0851EN | 5-Methyl-1-(2-methylphenyl)-N-quinolin-2-yltriazole-4-carboxamide | 1mg | $166 | 2021-12-16 | Buy |
| Arctom | HY-133180 | YW1128 99.38% | 5mg | $195 | 2026-05-26 | Buy |
| Arctom | HY-133180 | YW1128 99.38% | 10mM*1mLinDMSO(Solid+Solvent) | $204 | 2026-05-26 | Buy |
| Arctom | HY-133180 | YW1128 99.38% | 10mM*1mLinDMSO(Solution) | $214 | 2026-05-26 | Buy |
| Arctom | HY-133180 | YW1128 99.38% | 10mg | $314 | 2026-05-26 | Buy |
| Arctom | HY-133180 | YW1128 99.38% | 25mg | $627 | 2026-05-26 | Buy |
| Arctom | HY-133180 | YW1128 99.38% | 50mg | $1003 | 2026-05-26 | Buy |
| Arctom | HY-133180 | YW1128 99.38% | 100mg | $1604 | 2026-05-26 | Buy |
| Biorbyt Ltd | orb611984 | YW1128 >98% | 250mg | $2395.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611984 | YW1128 >98% | 1g | $4766.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611984 | YW1128 >98% | 100mg | $1431.4 | 2021-12-16 | Buy |
| Cayman Chemical | 27450 | YW1128 ≥98% | 1mg | $69 | 2026-04-30 | Buy |
| Cayman Chemical | 27450 | YW1128 ≥98% | 5mg | $313 | 2026-04-30 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMF: 30mg/mL; DMSO: 30mg/mL; Ethanol: 30mg/mL; PBS (pH 7.2): 2mg/mL
form :A crystalline solid
color :White to off-white
solubility :DMF: 30mg/mL; DMSO: 30mg/mL; Ethanol: 30mg/mL; PBS (pH 7.2): 2mg/mL
form :A crystalline solid
color :White to off-white
Safety Information
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Description
YW1128 is an inhibitor of Wnt/β-catenin signaling with an IC50 value of 4.1 nM in a reporter assay. It decreases protein levels of β-catenin in the presence of the GSK3β inhibitor lithium chloride and increases protein levels of Axin1 in HEK293 cells. YW1128 decreases lipid accumulation and the expression of gluconeogenic and lipogenic genes in Huh7 cells. It decreases the hepatic expression of Wnt target genes, improves glucose tolerance, and prevents body weight increases and hepatic lipid accumulation in mice fed a high-fat diet, but not mice fed normal chow, when administered at a dose of 40 mg/kg every other day for 11 weeks.Related product price
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