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1173908-52-5

Ethyl 8-chloro-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylate synthesis

1synthesis methods
17159-79-4 Synthesis
Ethyl 4-oxocyclohexanecarboxylate

17159-79-4
322 suppliers
$5.00/1g

41052-75-9 Synthesis
2-Chlorophenylhydrazine hydrochloride

41052-75-9
247 suppliers
$5.00/5g

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Yield:1173908-52-5 55%

Reaction Conditions:

Acidic conditions;Reflux;Fischer Indole Synthesis;

References:

Yin, Zhou;Whittell, Louise R.;Wang, Yao;Jergic, Slobodan;Liu, Michael;Harry, Elizabeth J.;Dixon, Nicholas E.;Beck, Jennifer L.;Kelso, Michael J.;Oakley, Aaron J. [Journal of Medicinal Chemistry,2014,vol. 57,# 6,p. 2799 - 2806] Location in patent:supporting information