METHYL 6-(4-(TERT-BUTOXYCARBONYL)PIPERAZIN-1-YL)PYRAZINE-2-CARBOXYLATE synthesis
- Product Name:METHYL 6-(4-(TERT-BUTOXYCARBONYL)PIPERAZIN-1-YL)PYRAZINE-2-CARBOXYLATE
- CAS Number:1375702-27-4
- Molecular formula:C15H22N4O4
- Molecular Weight:322.36
57260-71-6
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Yield:1375702-27-4 77%
Reaction Conditions:
with [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(ll) dichloride;caesium carbonate in 1,2-dimethoxyethane at 60 - 80;Inert atmosphere;Buchwald-Hartwig Coupling;
References:
Suwal, Sujit;Rahman, Mahmuda;O'Brien, Gregory;Karambizi, Victoire G.;Wrotny, Matthew;Scott Goodman [New Journal of Chemistry,2022,vol. 46,# 6,p. 2605 - 2608] Location in patent:supporting information