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145324-80-7

1H-Pyrazole-5-carboxylic acid, 3-methyl-1-(phenylmethyl)-, methyl ester synthesis

3synthesis methods
-

Yield:145324-80-7 833 mg

Reaction Conditions:

with potassium carbonate in N,N-dimethyl-formamide at 50; for 20 h;

References:

Henke, Brad R.;Aquino, Christopher J.;Birkemo, Larry S.;Croom, Dallas K.;Dougherty Jr., Robert W.;Ervin, Gregory N.;Grizzle, Mary K.;Hirst, Gavin C.;James, Michael K.;Johnson, Michael F.;Queen, Kennedy L.;Sherrill, Ronald G.;Sugg, Elizabeth E.;Suh, Edward M.;Szewczyk, Jerzy W.;Unwalla, Rayomand J.;Yingling, Jeff;Willson, Timothy M. [Journal of Medicinal Chemistry,1997,vol. 40,# 17,p. 2706 - 2725]