Antioxidant HP136,2(3H)-Benzofuranone,5,7-bis(1,1-dimethylethyl)-3-(3,4-dimethylphenyl) synthesis
- Product Name:Antioxidant HP136,2(3H)-Benzofuranone,5,7-bis(1,1-dimethylethyl)-3-(3,4-dimethylphenyl)
- CAS Number:164391-52-0
- Molecular formula:C24H30O2
- Molecular Weight:350.49
95-47-6
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96-76-4
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298-12-4
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164391-52-0
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Yield:164391-52-0 98%
Reaction Conditions:
with nickel(II) triflate;toluene-4-sulfonic acid for 24 h;Inert atmosphere;Heating;Green chemistry;Temperature;Time;
Steps:
1-11 Example 3
10 g of 2,4-di-tert-butylphenol was added to a 1000 mL three-necked flask. Glyoxylic acid 80mL, O-xylene 170mL, 250 mg of p-toluenesulfonic acid, 3.57 g of nickel triflate, Vacuuming backfilling nitrogen, The pump is depressurized, the temperature is slowly increased to 1600 ° C, and the reaction is 24 h. Distilling o-xylene under reduced pressure, Cool down to 70 ° C, Add 400 mL of methanol dropwise, A deep red solid precipitated while stirring. Filtering, Rinse with methanol, The obtained crude product was dissolved in dichloromethane and then recrystallized by dropwise addition of methanol. Obtained 122 g of a white solid. The yield was 98%.
References:
CN109651314,2019,A Location in patent:Paragraph 0012; 0015-0036
96-76-4
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164391-52-0
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5973-71-7
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164391-52-0
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![Phenol, 2-[(dimethylamino)(3,4-dimethylphenyl)methyl]-4,6-bis(1,1-dimethylethyl)-](/CAS/20210305/GIF/252961-08-3.gif)
252961-08-3
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164391-52-0
58 suppliers
$17.00/5g