4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)CHLOROBENZENE synthesis
- Product Name:4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)CHLOROBENZENE
- CAS Number:195062-61-4
- Molecular formula:C12H16BClO2
- Molecular Weight:238.52
76-09-5
404 suppliers
$8.20/250mg
1679-18-1
629 suppliers
$10.00/1g
195062-61-4
138 suppliers
$8.00/1g
Yield: 92%
Reaction Conditions:
with magnesium sulfate in diethyl ether at 20; for 16 h;Inert atmosphere;Schlenk technique;
Steps:
Synthesis of Pinacol Boronic Esters from Boronic Acids; General Procedure (GP1)
General procedure: A mixture of boronic acid (1.0 equiv), pinacol (1.0 equiv) and anhydrous MgSO4 (4.0 equiv) in Et2O (0.5 M) was stirred at r.t. for 16 h. The reaction mixture was filtered and the solvent removed in vacuo. The crude material was purified by distillation or flash column chromatography to give the pure boronic ester.
References:
Casoni, Giorgia;Myers, Eddie L.;Aggarwal, Varinder K. [Synthesis,2016,vol. 48,# 19,art. no. SS-2016-C0356-OP,p. 3241 - 3253]
637-87-6
305 suppliers
$38.00/10 G
73183-34-3
591 suppliers
$6.00/5g
195062-61-4
138 suppliers
$8.00/1g
106-47-8
483 suppliers
$5.00/5 g
73183-34-3
591 suppliers
$6.00/5g
195062-61-4
138 suppliers
$8.00/1g
637-87-6
305 suppliers
$38.00/10 G
![Bis[(pinacolato)boryl]Methane](/CAS/GIF/78782-17-9.gif)
78782-17-9
116 suppliers
$22.00/1g
195062-61-4
138 suppliers
$8.00/1g
106-39-8
478 suppliers
$14.00/5g
73183-34-3
591 suppliers
$6.00/5g
195062-61-4
138 suppliers
$8.00/1g