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ChemicalBook CAS DataBase List 1H-Indazole-5-carbonitrile,7-fluoro-(9CI)
633327-24-9

1H-Indazole-5-carbonitrile,7-fluoro-(9CI) synthesis

5synthesis methods
633327-22-7 Synthesis
5-BROMO-2,3-DIFLUORO-BENZALDEHYDE

633327-22-7
81 suppliers
$10.00/100mg

1H-Indazole-5-carbonitrile,7-fluoro-(9CI)

633327-24-9
12 suppliers
inquiry

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Yield:-

Steps:

Multi-step reaction with 4 steps
1: potassium carbonate / 1,2-dimethoxyethane / 12 h / 60 °C
2: hydrazine / tetrahydrofuran / 48 h / 90 °C
3: toluene-4-sulfonic acid / dichloromethane / 2 h / 20 °C
4: tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide / 12 h / 120 °C

References:

SAVIRA PHARMACEUTICALS GMBH;EUROPEAN MOLECULAR BIOLOGY LABORATORY;TAN, Xuefei;LIU, Yongfu;WU, Jun;ZBINDEN, Katrin Groebke;KUHN, Bernd;TANG, Guozhi;WU, Guolong;WANG, Lisha;SHEN, Hong;SHI, Tianlai;QIU, Zongxing WO2017/133670, 2017, A1

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