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ChemicalBook CAS DataBase List 2-(3-fluorophenoxy)benzoic acid
2795-62-2

2-(3-fluorophenoxy)benzoic acid synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 110 °C
2: potassium hydroxide; dihydrogen peroxide / methanol; ethanol / 4 h / 60 °C / Cooling with ice

References:

Li, Yi-Tao;Yao, Wen-Qiang;Zhou, Si;Xu, Jun-Xing;Lu, Hui;Lin, Jian;Hu, Xiao-Yun;Zhang, Shao-Kai [Bioorganic and Medicinal Chemistry Letters,2021,vol. 34]