Carbamic acid, [(1R,3S)-3-(aminomethyl)cyclopentyl]-, 1,1-dimethylethyl ester synthesis
- Product Name:Carbamic acid, [(1R,3S)-3-(aminomethyl)cyclopentyl]-, 1,1-dimethylethyl ester
- CAS Number:347185-71-1
- Molecular formula:C11H22N2O2
- Molecular Weight:214.3
![CarbaMic acid, N-[(1R,3S)-3-(azidoMethyl)cyclopentyl]-, 1,1-diMethylethyl ester](/CAS/20150408/GIF/347185-70-0.gif)
347185-70-0
3 suppliers
inquiry
347185-71-1
8 suppliers
inquiry
Yield:347185-71-1 100%
Reaction Conditions:
with hydrogen;5%-palladium/activated carbon in methanol;
Steps:
9.2
Step 2; (1S, 3R)-3-N-BOC-Aminocyclopentylmethylamine; The azide (6.0 g, 25.0 mmol) from Step 1 dissolved in methanol (150 ml) was reduced with 5 % Pd/C (300 mg) as described in Intermediate 5, Step 2 to give 5.35 g (100 %) of the amine as a semisolid, which was used as such for the coupling reaction.
References:
WO2005/75426,2005,A1 Location in patent:Page/Page column 29
![CarbaMic acid, N-[(1R,3S)-3-[[(Methylsulfonyl)oxy]Methyl]cyclopentyl]-, 1,1-diMethylethyl ester](/CAS/20150408/GIF/862700-29-6.gif)
862700-29-6
5 suppliers
inquiry
347185-71-1
8 suppliers
inquiry