4-(1-PYRROLIDINO)BENZALDEHYDE synthesis
- Product Name:4-(1-PYRROLIDINO)BENZALDEHYDE
- CAS Number:51980-54-2
- Molecular formula:C11H13NO
- Molecular Weight:175.23
123-75-1
577 suppliers
$10.00/5g
104-88-1
638 suppliers
$5.00/25g
51980-54-2
141 suppliers
$13.00/1g
Yield: 89%
Reaction Conditions:
with potassium phosphate;benzoin oxime;copper diacetate in dimethyl sulfoxide at 80;Inert atmosphere;
Steps:
General Procedure for Catalytic Experiments
General procedure: K3PO4 (5.62 mmol) in DMSO (4 mL), were added Cu(OAc)2 (0.28 mmol). The flask was evacuatedand backfilled with argon for three times. The resulting suspension was heated in a 80 °C oil bathwith stirring for the indicated time. The reactor was cooled to r.t., the flask was opened to air and thereaction mixture was poured into water (20 mL), extracted with ethyl acetate (20 mL × 3), andorganic layer was washed with water (20 mL × 2) and once with brine (25 mL), dried overmagnesium sulfate and concentrated in vacuo. The product was purified by column chromatographyon silica gel using petroleum ether and ethyl acetate as eluent.1-(2-Methoxyphenyl)-1H-pyrrole (3a) [30]: colorless oil (0.43 g, 88%). 1H-NMR (400 MHz, CDCl3) δ (ppm):7.30-7.23 (2H, m), 7.03-6.98 (4H, m), 6.30 (2H,
References:
Yuan, Chunling;Zhang, Lei;Zhao, Yingdai [Molecules,2019,vol. 24,# 22,art. no. 4177]
123-75-1
577 suppliers
$10.00/5g
459-57-4
603 suppliers
$6.00/25g
51980-54-2
141 suppliers
$13.00/1g
123-75-1
577 suppliers
$10.00/5g
1122-91-4
703 suppliers
$9.00/10g
51980-54-2
141 suppliers
$13.00/1g
62-53-3
679 suppliers
$10.00/1g
51980-54-2
141 suppliers
$13.00/1g
4096-21-3
99 suppliers
$15.00/250mg
93-61-8
299 suppliers
$10.00/5 g
51980-54-2
141 suppliers
$13.00/1g