3-(4-Chlorophenyl)tricyclo[3.3.1.13,7]decane-1-carboxylic acid synthesis
- Product Name:3-(4-Chlorophenyl)tricyclo[3.3.1.13,7]decane-1-carboxylic acid
- CAS Number:56531-62-5
- Molecular formula:C17H19ClO2
- Molecular Weight:290.78
21816-08-0
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Yield:56531-62-5 81%
Reaction Conditions:
with aluminum (III) chloride for 6 h;Inert atmosphere;Reflux;
References:
Plewe, Michael B.;Sokolova, Nadezda V.;Gantla, Vidyasagar Reddy;Brown, Eric R.;Naik, Shibani;Fetsko, Alexandra;Lorimer, Donald D.;Lorimer, Donald D.;Dranow, David M.;Dranow, David M.;Smutney, Hayden;Smutney, Hayden;Bullen, Jameson;Bullen, Jameson;Sidhu, Rana;Sidhu, Rana;Master, Arshil;Master, Arshil;Wang, Junru;Wang, Junru;Kallel, E. Adam;Zhang, Lihong;Kalveram, Birte;Freiberg, Alexander N.;Henkel, Greg;McCormack, Ken [ACS Medicinal Chemistry Letters,2020,vol. 11,# 6,p. 1160 - 1167] Location in patent:supporting information