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780721-69-9

Benzenepropanoic acid, β-amino-α-hydroxy-, methyl ester synthesis

1synthesis methods
tert-butyl 2-oxo-1-phenylethylcarbamate

140196-38-9
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Benzenepropanoic acid, β-amino-α-hydroxy-, methyl ester

780721-69-9
2 suppliers
inquiry

-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: Et3N / CH2Cl2 / Ambient temperature
2: Et3N / 36 h / Ambient temperature
3: 1.) 6N aq. HCl, 2.) SOCl2 / 1.) 110 deg C, 12 h, 2.) RT, 12 h

References:

Barco, Achille;Benetti, Simonetta;De Risi, Carmela;Pollini, Gian P.;Spalluto, Giampiero;Zanirato, Vinicio [Tetrahedron,1996,vol. 52,# 13,p. 4719 - 4734]