Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
logo
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook

Welcome back!

Structured search
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
ChemicalBook CAS DataBase List 1,3,8-Trihydroxy-11H-benzofuro[2,3-b][1]benzopyran-11-one
98094-87-2

1,3,8-Trihydroxy-11H-benzofuro[2,3-b][1]benzopyran-11-one synthesis

13synthesis methods
2'-HYDROXYGENISTEIN

1156-78-1
69 suppliers
inquiry

1,3,8-Trihydroxy-11H-benzofuro[2,3-b][1]benzopyran-11-one

98094-87-2
11 suppliers
inquiry

-

Yield:98094-87-2 66%

Reaction Conditions:

with 2,3-dicyano-5,6-dichloro-p-benzoquinone in tetrahydrofuran at 60; for 0.75 h;Inert atmosphere;

Steps:

4.2.6. Lupinalbin A (3)23

DDQ (79.0 mg, 0.349 mmol) was added under N2 to a solution of 4 (100 mg, 0.35 mmol) in THF (20 mL). The reaction mixture was heated to 60 °C with stirring for 15 min. Additional DDQ (79.0 mg, 0.349 mmol) was added to the mixture and stirring was continued at the same temperature for 30 min. The solvent was evaporated and the crude mixture purified by column chromatography using Hex/EtOAc as eluent to give coumaronochromone 3 (66 mg, 66%) as a white solid: 3 was recrystallized from Hex/EtOAc (1:4) to afford white needle-like crystals, which decomposed at 278.4-280.0 °C (lit.refPreviewPlaceHolder14 mp >300 °C); IR (neat) νmax 3327, 3101, 2922, 1622, 1436, 1029, 822 cm-1; 1H NMR (CD3OD, 400 MHz) δ 7.75 (1H, d, J=8.4 Hz, H-6'), 6.99 (1H, d, J=1.9 Hz, H-3'), 6.89 (1H, dd, J=1.9 and 8.4 Hz, H-5'), 6.46 (1H, d, J=2.0 Hz, H-8), 6.27 (1H, d, J=2.0 Hz, H-6); 13C NMR (CD3OD, 100 MHz) δ 180.0 (C, C-4), 166.2 (C, C-2), 165.2 (C, C-7), 164.0 (C, C-5), 157.8 (C, C-4'), 156.6 (C, C-8a), 151.9 (C, C-2'), 122.5 (CH, C-6'), 115.2 (CH, C-5'), 114.7 (C, C-1'), 104.5 (C, C-4a), 100.9 (CH, C-6), 99.5 (C, C-3), 98.7 (CH, C-3'), 95.8 (CH, C-8); HRMS-ESI m/z [M-H]- calcd for C15H7O6 283.0243, found 283.0239.

References:

Selepe, Mamoalosi A.;Drewes, Siegfried E.;Van Heerden, Fanie R. [Tetrahedron,2011,vol. 67,# 45,p. 8654 - 8658] Location in patent:experimental part

Ethanone, 1-[2-(methoxymethoxy)-4,6-bis(phenylmethoxy)phenyl]-

67052-53-3
0 suppliers
inquiry

1,3,8-Trihydroxy-11H-benzofuro[2,3-b][1]benzopyran-11-one

98094-87-2
11 suppliers
inquiry

References
4H-1-Benzopyran-4-one, 3-[2,4-bis(phenylmethoxy)phenyl]-5,7-bis(phenylmethoxy)-

82458-45-5
0 suppliers
inquiry

1,3,8-Trihydroxy-11H-benzofuro[2,3-b][1]benzopyran-11-one

98094-87-2
11 suppliers
inquiry

References
2-Propen-1-one, 3-[2,4-bis(phenylmethoxy)phenyl]-1-[2-hydroxy-4,6-bis(phenylmethoxy)phenyl]-, (E)- (9CI)

120980-05-4
0 suppliers
inquiry

1,3,8-Trihydroxy-11H-benzofuro[2,3-b][1]benzopyran-11-one

98094-87-2
11 suppliers
inquiry

References
2-Propen-1-one, 1-[2-(acetyloxy)-4,6-bis(phenylmethoxy)phenyl]-3-[2,4-bis(phenylmethoxy)phenyl]-, (2E)-

369371-85-7
0 suppliers
inquiry

1,3,8-Trihydroxy-11H-benzofuro[2,3-b][1]benzopyran-11-one

98094-87-2
11 suppliers
inquiry

References