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ChemicalBook CAS DataBase List Acitretin Impurity
1621284-00-1

Acitretin Impurity synthesis

7synthesis methods
BONIYDFKKJJFBB-CDKJVOIVSA-N

1269259-99-5
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Acitretin Impurity

1621284-00-1
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: lithium aluminium tetrahydride; aluminum (III) chloride / tetrahydrofuran / 24 h / 0 - 20 °C
2: sodium carbonate; manganese(IV) oxide / dichloromethane / 48 h / 20 °C
3: zinc; titanium tetrachloride / tetrahydrofuran / 3.5 h / 0 °C / Inert atmosphere; Reflux

References:

Kang, Yan-Fei;Yan, Wen-Jing;Zhou, Ting-Wen;Dai, Fang;Li, Xiu-Zhuang;Bao, Xia-Zhen;Du, Yu-Ting;Yuan, Cui-Hong;Wang, Hai-Bo;Ren, Xiao-Rong;Liu, Qiang;Jin, Xiao-Ling;Zhou, Bo;Zhang, Jie [Chemistry - A European Journal,2014,vol. 20,# 29,p. 8904 - 8908]