Benzobarbital synthesis
1synthesis methods
- Product Name:Benzobarbital
- CAS Number:744-80-9
- Molecular formula:C19H16N2O4
- Molecular Weight:336.34
Phenobarbital was synthesized using silver salt of phenobarbital and benzoyl chloride in catalyst-free reaction with about 20% yield. Benzoylphenobarbital was synthesized from phenobarbital and benzoyl chloride using 4 dimethylaminopyridine (abbreviated a
Yield:744-80-9 60%
Reaction Conditions:
at 155 - 170; for 9 h;
References:
Frangulyan, G. A.;Vinograd, L. Kh.;D'yachkova, S. N. [Pharmaceutical Chemistry Journal,1980,vol. 14,# 3,p. 203 - 204][Khimiko-Farmatsevticheskii Zhurnal,1980,vol. 14,# 3,p. 102 - 103]