bis(4-chloro-3-nitrophenyl) sulphone synthesis
- Product Name:bis(4-chloro-3-nitrophenyl) sulphone
- CAS Number:1759-05-3
- Molecular formula:C12H6Cl2N2O6S
- Molecular Weight:377.16
80-07-9
340 suppliers
$6.00/25g
1759-05-3
26 suppliers
$172.00/50MG
Yield:1759-05-3 99%
Reaction Conditions:
with sulfuric acid;nitric acid in 1,2-dichloro-ethane;
Steps:
1 EXAMPLE 1
EXAMPLE 1 57.4 g (0.2 moles) of 4,4'-dichloro diphenylsulfone is dissolved in 170 ml of 1,2-dichloro ethane. Following addition of 28.2 g of nitric acid (specific gravity 1.50) at room temperature, to the resultant mixture there is added 98% sulfuric acid dropwise during 30 minutes at 30°-40° C. After stirring for 7 hours at 70°-80° C., the mixture is cooled and then separated into an organic layer and a mixed acid layer. The solvent is removed by steam distillation. The precipitate is filtered, washed with water and dried to give needle-like crystals of 3,3'-dinitro-4,4'-dichloro diphenylsulfone (74.6 g). Yield 99%. Purity determined by high performance liquid chromatography is 99.6%. Melting point 201°-202° C. By recrystallization from ethanol there is obtained needle-like pure crystals. M.P. 201°-202° C.
References:
US4482742,1984,A
108-90-7
685 suppliers
$10.00/25G
1759-05-3
26 suppliers
$172.00/50MG
98-60-2
338 suppliers
$5.00/5g
1759-05-3
26 suppliers
$172.00/50MG