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ChemicalBook CAS DataBase List BOC-ALA-ALA-PNA
50439-35-5

BOC-ALA-ALA-PNA synthesis

4synthesis methods
L-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-, 5-[[bis[[(phenylmethoxy)carbonyl]amino]methylene]amino]-2-naphthalenyl ester

221017-30-7
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: 85 percent / H2 / 10 percent Pd/C / ethanol; diethyl ether / Ambient temperature
2: 75 percent / 3-morpholino-1-propanesulfonate, CaCl2 (pH 8.0) / dimethylsulfoxide / 12 h / 25 °C / trypsin

References:

Sekizaki, Haruo;Itoh, Kunihiko;Toyota, Eiko;Tanizawa, Kazutaka [Chemical and Pharmaceutical Bulletin,1999,vol. 47,# 1,p. 104 - 110]

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