BUMINAFOS synthesis
1synthesis methods
- Product Name:BUMINAFOS
- CAS Number:51249-05-9
- Molecular formula:C18H38NO3P
- Molecular Weight:347.47
Buminafos is commercially synthesised through esterification of a cyclohexylphosphonic acid derivative with butanol. The production process begins with the preparation of a cyclohexylamine intermediate, which is reacted with phosphorus oxychloride to form a phosphonic acid derivative. This intermediate undergoes esterification with butanol in the presence of a catalyst to yield the dibutyl ester form of buminafos. The reaction is carried out under controlled temperature and pH conditions to ensure high yield and purity.
Yield:-
Reaction Conditions:
at 70;
References:
Wieczorek;Gancarz;Bielecki;Grzys;Sarapuk [Phosphorus, Sulfur and Silicon and the Related Elements,2001,vol. 174,p. 119 - 128]