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ChemicalBook CAS DataBase List Ceftezole Impurity 22
43194-95-2

Ceftezole Impurity 22 synthesis

3synthesis methods
-

Yield:43194-95-2 96%

Steps:

4

Example 4; 4-[5-amino-l-(2,6-difluoro-benzoyl)-lH-[l,2,4]triazol-3- ylamino]-N-(2-tetrazol-l-yl-acetyl)-benzenesulfonamide (Cpd4); 4a; EPO Using the mixed anhydride formation procedure, 1.6 g (96 %) of Compound 4a was generated from tetraazolylacetic acid (1.0 g) and pivaloyl chloride (1.0 g). 1H NMR (300 MHz, CDCCl3) δ 8.90 (s, 1 H), 5.45 (s, 2 H), 1.21 (s, 9 H).

References:

WO2006/42215,2006,A1 Location in patent:Page/Page column 35-36

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