Cyclohexaneethanol, 1-(hydroxymethyl)- synthesis

4synthesis methods

Yield:-

Steps:

Multi-step reaction with 2 steps
1: H₂SO₄ / benzene / 36 h / Heating
2: LAH / diethyl ether; tetrahydrofuran / 48 h / Heating

References:

Scott;Moore;Zalucky;Nicholson;Lee;Hinko [Journal of Medicinal Chemistry,1985,vol. 28,# 4,p. 413 - 417]

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