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ChemicalBook CAS DataBase List ETHYL 2-HYDROXY-4-PHENYLPYRIMIDINE-5-CARBOXYLATE
188781-06-8

ETHYL 2-HYDROXY-4-PHENYLPYRIMIDINE-5-CARBOXYLATE synthesis

3synthesis methods
Benzenepropanoic acid, α-[[(aminocarbonyl)amino]methylene]-β-oxo-, ethyl ester

188781-04-6
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ETHYL 2-HYDROXY-4-PHENYLPYRIMIDINE-5-CARBOXYLATE

188781-06-8
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Yield:188781-06-8 65%

Reaction Conditions:

with sodium ethanolate in ethanol at 20;Cyclization;

References:

Palanki;Erdman;Gayo-Fung;Shevlin;Sullivan;Goldman;Ransone;Bennett;Manning;Suto [Journal of medicinal chemistry,2000,vol. 43,# 21,p. 3995 - 4004]