ChemicalBook CAS DataBase List Fenoxanil

Fenoxanil synthesis

1synthesis methods

Product Name:Fenoxanil
CAS Number:115852-48-7
Molecular formula:C15H18Cl2N2O2
Molecular Weight:329.22

The industrial production of fenoxanil involves the preparation of 2-(2,4-dichlorophenoxy)propionic acid, which is activated for amide formation. This intermediate is then reacted with 1-cyano-1,2-dimethylpropylamine under controlled conditions to form the final compound. The synthesis is optimized for regioselectivity and purity.

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773837-37-9 Synthesis

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2-(2,4-dichlorophenoxy)propanoyl chloride

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Yield:-

Reaction Conditions:

Stage #1:3-methyl-butan-2-one;sodium cyanide with ammonium chloride
Stage #2:2-(2,4-dichloro-phenoxy)-propionyl chloride

References:

Jiangsu Changqing Agrochemical Co., Ltd.;Yu Guoquan;Ding Huaping;Ji Zhiyang;Wang Xin CN106008263, 2016, A Location in patent:Paragraph 0007-0009

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