Labetalol EP impurity D synthesis

1synthesis methods

Yield:32780-65-7 62%

Reaction Conditions:

with ammonium hydroxide for 192 h;Ambient temperature;

References:

Clifton;Collins;Hallett;Hartley;Lunts;Wicks [Journal of Medicinal Chemistry,1982,vol. 25,# 6,p. 670 - 679]

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