Methyl 2-amino-4,5-dimethoxybenzoate synthesis
- Product Name:Methyl 2-amino-4,5-dimethoxybenzoate
- CAS Number:26759-46-6
- Molecular formula:C10H13NO4
- Molecular Weight:211.21
26791-93-5
151 suppliers
$10.00/1g
26759-46-6
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$6.00/5g
Yield:26759-46-6 97%
Reaction Conditions:
with palladium 10% on activated carbon;hydrogen in ethyl acetate at 25; under 775.743 Torr; for 16 h;
Steps:
1.3
Step 3: A mixture of c (1.0 g, 4.1 mmol, 1.0 eq) and Pd/C (10% wt., 300 mg) in EtOAc (15.0 mL) was stirred at 25 oC under H2 (15 psi) atmosphere for 16 hours. The reaction mixture was filtered through celite and the filter cake washed with EtOAc (20 mL). The filtrate was concentrated to afford d (840 mg, 97%) as a light yellow solid.1H NMR (400 MHz, DMSO- d6): d 7.12 (s, 1H), 6.45 (s, 2 H), 6.36 (s, 1H), 3.74 (s, 6 H), 3.64 (s, 3 H).
References:
SILICON SWAT, INC.;ALLEN, Bryce K.;CHAMBERLAIN, Brian T.;DWIGHT, Timothy A.;HUANG, Huang;LIN, Zhixiong;MARINO, Kristen A.;NIU, Deqiang;SHECHTER, Sharon;SWANN, Steven WO2020/232375, 2020, A1 Location in patent:Page/Page column 99-100
2150-38-1
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$10.00/1g
26759-46-6
211 suppliers
$6.00/5g
93-07-2
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$5.00/5g
26759-46-6
211 suppliers
$6.00/5g
67-56-1
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$7.30/5ml-f
5653-40-7
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$12.50/5 g
26759-46-6
211 suppliers
$6.00/5g