N-(tert-butyl)-1H-indazole-7-carboxamide synthesis
- Product Name:N-(tert-butyl)-1H-indazole-7-carboxamide
- CAS Number:1476776-76-7
- Molecular formula:C12H15N3O
- Molecular Weight:217.27
677304-69-7
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1476776-76-7
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Yield: 86%
Reaction Conditions:
Stage #1:1H-indazole-7-carboxylic acid with 1,1'-carbonyldiimidazole in N,N-dimethyl-formamide at 20 - 25; for 0.916667 h;Inert atmosphere;
Stage #2:tert-butylamine in N,N-dimethyl-formamide at 21 - 38; for 3.21667 h;Inert atmosphere;
References:
Chung, Cheol K.;Bulger, Paul G.;Kosjek, Birgit;Belyk, Kevin M.;Rivera, Nelo;Scott, Mark E.;Humphrey, Guy R.;Limanto, John;Bachert, Donald C.;Emerson, Khateeta M. [Organic Process Research and Development,2014,vol. 18,# 1,p. 215 - 227]