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ChemicalBook CAS DataBase List (S)-(-)-1-AMINO-2-(METHOXYMETHYL)PYRROLIDINE
59983-39-0

(S)-(-)-1-AMINO-2-(METHOXYMETHYL)PYRROLIDINE synthesis

9synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 1) lithium diisopropylamide / 1) ether, 0 deg C, 4 h, 2) -78 deg C, 2 h; 10 h, -78 deg C to RT
2: O3 / pentane / -78 °C
3: LiAlH4 / tetrahydrofuran

References:

Enders, Dieter;Lohray, Braj Bhushan [Angewandte Chemie,1987,vol. 99,# 4,p. 359 - 360]

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