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ChemicalBook CAS DataBase List TEPP
107-49-3

TEPP synthesis

9synthesis methods
Tetraethyl pyrophosphate is commercially synthesised by condensing triethyl phosphate with phosphorus oxychloride. The production process involves the controlled esterification of phosphorus oxychloride with triethyl phosphate or ethanol in the presence of a base, typically under anhydrous conditions to prevent hydrolysis. This yields tetraethyl diphosphate.
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Yield:107-49-3 92%

Reaction Conditions:

with silver(l) oxide in acetonitrile at 20; for 49 h;

References:

Furuta, Toshiaki;Torigai, Hiromi;Osawa, Tomoko;Iwamura, Michiko [Journal of the Chemical Society. Perkin transactions I,1993,# 24,p. 3139 - 3142]

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