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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
ChemicalBook CAS DataBase List Uniconazole
83657-22-1

Uniconazole synthesis

6synthesis methods
The commercial production of uniconazole typically involves a multi-step synthesis starting with pinacolone as a key intermediate. This compound undergoes a condensation reaction with 4-chlorobenzaldehyde to form a substituted penten-3-ol backbone. The next step introduces a triazole ring via nucleophilic substitution using 1,2,4-triazole, forming the core structure of uniconazole. The final step involves stereoselective purification to isolate the biologically active enantiomer, Uniconazole-P, which is responsible for its plant growth-regulating properties.
5469-26-1 Synthesis
1-Bromopinacolone

5469-26-1
183 suppliers
$12.00/1g

Uniconazole

83657-22-1
264 suppliers
$25.00/1g

-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: K2CO3 / acetone
2: morpholine, AcOH / benzene
3: NaBH4 / methanol

References:

Min, Yong Ki;Asami, Tadao;Fujioka, Shozo;Murofushi, Noboru;Yamaguchi, Isomaro;Yoshida, Shigeo [Bioorganic and Medicinal Chemistry Letters,1999,vol. 9,# 3,p. 425 - 430]

78603-97-1 Synthesis
(S)-(-)-2-AMINO-4-METHYL-1,1-DIPHENYL-1-PENTANOL

78603-97-1
24 suppliers
$174.00/1g

1-Penten-3-one, 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)-, (1E)-

76713-89-8
1 suppliers
inquiry

Uniconazole

83657-22-1
264 suppliers
$25.00/1g

References
29194-04-5 Synthesis
2-(benzyl(methyl)amino)-1-phenylethanol

29194-04-5
25 suppliers
$20.00/100mg

N-Ethylaniline

103-69-5
274 suppliers
$13.00/100g

1-Penten-3-one, 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)-, (1E)-

76713-89-8
1 suppliers
inquiry

Uniconazole

83657-22-1
264 suppliers
$25.00/1g

References
Diethyl ether

60-29-7
0 suppliers
$30.00/50g

552-79-4 Synthesis
(-)-N-METHYLEPHEDRINE

552-79-4
0 suppliers
$33.30/1g

N-Ethylaniline

103-69-5
274 suppliers
$13.00/100g

1-Penten-3-one, 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)-, (1E)-

76713-89-8
1 suppliers
inquiry

Uniconazole

83657-22-1
264 suppliers
$25.00/1g

References
1-Penten-3-one, 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)-

69753-20-4
1 suppliers
inquiry

Uniconazole

83657-22-1
264 suppliers
$25.00/1g

References

Uniconazole Related Search:

Dimethyl sebacate Dimethyl carbonate Diniconazole Dimethyl phthalate Dimethyl ether Tetraphenylcyclopentadienone 4,4'-Diphenylmethane diisocyanate Dimethyl sulfoxide Choline Fenofibrate Darunavir ethanolate