| Identification | Back Directory | [Name]
Kushenol L | [CAS]
101236-50-4 | [Synonyms]
Kushenol L
product/154902
4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-6,8-bis(3-methyl-2-buten-1-yl)-, (2R,3R)- | [Molecular Formula]
C25H28O7 | [MDL Number]
MFCD21333762 | [MOL File]
101236-50-4.mol | [Molecular Weight]
440.49 |
| Chemical Properties | Back Directory | [Boiling point ]
715.7±60.0 °C(Predicted) | [density ]
1.334±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Cryst. | [pka]
8.04±0.60(Predicted) |
| Hazard Information | Back Directory | [Uses]
Kushenol L is one of the main components of EtOA cextracts from Kushen, a traditional medicinal herb derived from the dried roots of Sophora flavescens Ait. Kushenol L is a flavonoid and plays an important role in anti-diabeticeffects[1]. | [in vivo]
Kushenol L (1 mg/kg; oral) has a T1/2 of 2.26 hours, a Cmax of 24.17 μg/L and an AUC of 54035 μg/h?L in adult male Sprague-Dawley rats weighing 300 g[1].
| [References]
[1] Lei Chen, et al. An accurate and reproducible method for simultaneous determination of four flavonoids in EtOAc extracts from Sophora flavescens Ait. in rat plasma based on UHPLC Q-Exactive Mass spectrometry: Application to a pharmacokinetics study. Biomed Chromatogr. 2019 Mar;33(3):e4447. DOI:10.1002/bmc.4447 |
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BioBioPha Co., Ltd.
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0871-65217109 13211707573; |
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http://www.biobiopha.com |
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