| Identification | Back Directory | [Name]
Kushenol B | [CAS]
99217-64-8 | [Synonyms]
Kushenol B
(2S)-2-(2,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-6-(3-methyl-2-butenyl)-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexenyl]-4H-1-benzopyran-4-one | [Molecular Formula]
C30H36O6 | [MOL File]
99217-64-8.mol | [Molecular Weight]
492.6 |
| Chemical Properties | Back Directory | [Boiling point ]
702.3±60.0 °C(Predicted) | [density ]
1.198±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
8.19±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
Kushenol B is an isoprenoid flavonoid isolated from S. flavescens, has antimicrobial, anti-inflammatory and antioxidant activities[1]. Kushenol B has inhibitory activity against cAMP phosphodiesterase (PDE), with an IC50 of 31 μM[1]. | [References]
[1] Han-Tian Fan, et al. The rational search for PDE10A inhibitors from Sophora flavescens roots using pharmacophore? and docking?based virtual screening. Mol Med Rep DOI:10.3892/mmr.2017.7871 |
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