| Identification | Back Directory | [Name]
2,5-Dioxopyrrolidin-1-yl 3-methoxypropanoate | [CAS]
1027371-75-0 | [Synonyms]
m-PEG1-NHS ester
2,5-Dioxopyrrolidin-1-yl 3-methoxypropanoate
3-Methoxy-propionic acid 2,5-dioxo-pyrrolidin-1-yl ester | [Molecular Formula]
C8H11NO5 | [MDL Number]
MFCD20229579 | [MOL File]
1027371-75-0.mol | [Molecular Weight]
201.18 |
| Chemical Properties | Back Directory | [Boiling point ]
292.8±42.0 °C(Predicted) | [density ]
1.31±0.1 g/cm3(Predicted) | [solubility ]
Soluble in DCM | [form ]
Solid | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Description]
m-PEG1-NHS ester is a PEG linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
m-PEG1-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67. DOI:10.3762/bjoc.11.74 |
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