| Identification | Back Directory | [Name]
MPEG6-Mal | [CAS]
1644231-07-1 | [Synonyms]
MPEG6-Mal
mPEG6-Maleimide
m-PEG6-amino-Mal
m-PEG6-amido-Mal
Mal-amido-PEG6-Ome
1H-Pyrrole-1-propanamide, N-3,6,9,12,15,18-hexaoxanonadec-1-yl-2,5-dihydro-2,5-dioxo- | [Molecular Formula]
C20H34N2O9 | [MDL Number]
MFCD27977520 | [MOL File]
1644231-07-1.mol | [Molecular Weight]
446.49 |
| Hazard Information | Back Directory | [Description]
m-PEG6-Mal is a PEG linker containing a maleimide group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
m-PEG6-amino-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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