ChemicalBook--->CAS DataBase List--->1028206-58-7

1028206-58-7

1028206-58-7 Structure

1028206-58-7 Structure
IdentificationBack Directory
[Name]

SPhos Pd G1, Methyl t-Butyl Ether Adduct
[CAS]

1028206-58-7
[Synonyms]

SPhos precatalyst
SPhos Palladacycle
SPhos Pd G1, Methyl
SPhos Pd G1, Methyl t-Butyl Ether Adduct
Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)[2-(2-aminoethylphenyl)]palladium(II)
chloropalladium(1+),dicyclohexyl-[2-(2,6-dimethoxyphenyl)phenyl]phosphane,2-methoxy-2-methylpropane,2-phenylethanamine
Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)[2-(2-aminoethylphenyl)]palladium(II) methyl-t-butylether adduct,S
Chloro(2-dicyclohexylphosphino-2',6'-diMethoxy-1,1'-biphenyl)[2-(2-aMinoethylphenyl)]palladiuM(II) - Methyl-t-butyl ether adduct
Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)[2-(2-aminoethylphenyl)]palladium(II) methyl-t-butylether adduct, min. 98% 
Palladium(II) acetate/2-dicyclohexylphosphino-26dimethoxy-1,1-biphenyl/potassium phosphate admixture [Catkit single-use vials - 1.96 wt% Pd(OAc)2]
Chloro(2-dicyclohexylphosphino-2',6'-diMethoxy-1,1'-biphenyl)[2-(2-aMinoethylphenyl)]palladiuM(II) Methyl-t-butylether adduct,98% SPhos Palladacycle
Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)[2-(2-aminoethylphenyl)]palladium(II) methyl-t-butylether adduct, min. 98% [SPhos Palladacycle]
PalladiuM(II) acetate/2-dicyclohexylphosphino-2,6-diMethoxy-1,1'-biphenyl (SPhos)/potassiuM phosphate adMixture [CatKit single-use vials - 1.96 wt% Pd(OAc)2]
Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)[2-(2-aminoethylphenyl)]palladium(II) methyl-t-butylether adduct, min. 98% [SPhos Palladacycle Gen. 1]
[Molecular Formula]

C34H45ClNO2PPd
[MDL Number]

MFCD15144765
[MOL File]

1028206-58-7.mol
[Molecular Weight]

672.58
Chemical PropertiesBack Directory
[Melting point ]

176℃
[storage temp. ]

Inert atmosphere,Room Temperature
[form ]

Powder
[color ]

white
[InChIKey]

KKQLFRKFTOXIHZ-UHFFFAOYSA-N
[SMILES]

P(C1CCCCC1)(C1CCCCC1)([Pd+2]1(NCCC2=CC=CC=[C-]12)[Cl-])C1C=CC=CC=1C1C(=CC=CC=1OC)OC
Questions And AnswerBack Directory
[Appearance]

Solid
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

[Uses]

Chloro(2-dicyclohexylphosphino-2'',6''-dimethoxy-1,1''-biphenyl)[2-(2-aminoethylphenyl)]palladium(II) has been used as catalyst in, the studies of CDK 8/19 inhibitors: Discovery of novel and selective CDK8/19 dual inhibitors and elimination of their CYP3A4 time-dependent inhibition potential; ?Biaryl Phosphine Based Pd(II) Amido Complexes: The Effect of Ligand Structure on Reductive Elimination
[reaction suitability]

core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reaction type: Cross Couplings
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