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106881-54-3

106881-54-3 Structure

106881-54-3 Structure
IdentificationBack Directory
[Name]

BIM 21009
[CAS]

106881-54-3
[Synonyms]

BIM 21009
LHRHNcpapa
LHRH-Ncpapa
LHRH Ncpapa
[Molecular Formula]

C74H92ClN17O13
[MOL File]

106881-54-3.mol
[Molecular Weight]

1463.08
Chemical PropertiesBack Directory
[Sequence]

Ac-{d-Nal}-{d-Cl-Phe}-{d-Phe}-Ser-Tyr-{d-Arg}-Phe-Arg-Pro-{d-Ala}-NH2
Hazard InformationBack Directory
[Description]

Bim 21009 is a gonadorelin inhibitor.
[Uses]

BIM 21009 is a LHRH and GnRH receptor antagonist. BIM 21009 inhibits tumor growth[1].
[References]

[1] Ban E, Crumeyrolle-Arias M, Latouche J, Leblanc P, Heurtier JF, Drieu K, Fillion G, Haour F. GnRH receptors in rat brain, pituitary and testis; modulation following surgical and gonadotropin-releasing hormone agonist-induced castration. Mol Cell Endocrinol. 1990 Mar 26;70(1):99-107. DOI:10.1016/0303-7207(90)90063-e
[2] Bogden AE,et al. Treatment of R-3327 prostate tumors with a somatostatin analogue (somatuline) as adjuvant therapy following surgical castration. Cancer Res. 1990 May 1;50(9):2646-50. PMID:1970275
106881-54-3 suppliers list
Company Name: TargetMol Chemicals Inc.
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Website: https://www.targetmol.com/
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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