| Identification | Back Directory | [Name]
Proparyl-PEG5-methane | [CAS]
1101668-39-6 | [Synonyms]
mPEG4-Alkyne
mPEG4-Propyne
PROPARYL-PEG4-ME
m-PEG5-Propargyl
ROPARGYL-PEG5-METHANE
Proparyl-PEG5-methane
Propargyl-PEG5-methane
2,5,8,11,14-Pentaoxaheptadec-16-yne | [Molecular Formula]
C12H22O5 | [MDL Number]
MFCD28155212 | [MOL File]
1101668-39-6.mol | [Molecular Weight]
246.3 |
| Chemical Properties | Back Directory | [Boiling point ]
304.2±32.0 °C(Predicted) | [density ]
1.016±0.06 g/cm3(Predicted) | [storage temp. ]
Store at Room Tem. | [form ]
clear liquid | [color ]
Colorless to Light yellow |
| Hazard Information | Back Directory | [Description]
Propargyl-PEG5-methane has a propargyl group which can react with azide compounds via copper catalyzed Click Chemistry reactions. The PEG units increase water-solubility of the molecule. | [Uses]
m-PEG4-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67. DOI:10.3762/bjoc.11.74 |
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