| Identification | Back Directory | [Name]
Propargyl-succinimidyl-ester | [CAS]
1174157-65-3 | [Synonyms]
Alkyne-NHS ester
Propargyl-NHS Ester
Propargyl-PEG1-NHS este
Propargyl-dPEG??-NHS ester
Propargyl-succinimidyl-ester
Propargyl-N-hydroxysuccinimidyl ester
N-Succinimidyl 3-(propargyloxy)propionate
2,5-Dioxopyrrolidin-1-yl 3-(prop-2-ynyloxy)propanoate
2,5-dioxopyrrolidin-1-yl 3-(prop-2-yn-1-yloxy)propanoate
3-Propargyloxy-propanoic acid 2,5-dioxo-1-pyrrolidinyl ester
3-(2-Propyn-1-yloxy)propanoic acid 2,5-dioxo-1-pyrrolidinyl ester
3-(2-Propyn-1-yloxy)-2,5-dioxo-1-pyrrolidinyl Ester Propanoic Acid
Propanoic acid, 3-(2-propyn-1-yloxy)-, 2,5-dioxo-1-pyrrolidinyl ester | [Molecular Formula]
C10H11NO5 | [MDL Number]
MFCD13184973 | [MOL File]
1174157-65-3.mol | [Molecular Weight]
225.2 |
| Chemical Properties | Back Directory | [Melting point ]
36-41°C | [Boiling point ]
351.2±48.0 °C(Predicted) | [density ]
1.32±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Soluble in DMSO, DCM, DMF | [form ]
Solid | [color ]
Gray | [Appearance]
White solid | [Water Solubility ]
Slightly soluble in water. | [InChI]
1S/C10H11NO5/c1-2-6-15-7-5-10(14)16-11-8(12)3-4-9(11)13/h1H,3-7H2 | [InChIKey]
WKIKHHMUNOVQLD-UHFFFAOYSA-N | [SMILES]
C#CCOCCC(ON1C(CCC1=O)=O)=O |
| Hazard Information | Back Directory | [Description]
Propargyl-PEG1-NHS ester is an amine reactive reagent that can be used for derivatizing peptides, antibodies, amine coated surfaces etc. The alkyne group reacts with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions. | [Uses]
N-Succinimidyl 3-(propargyloxy)propionate is an acetylene-containing reagent with NHS ester functionality for reaction with amines. | [Uses]
Propargyl-N-hydroxysuccinimidyl ester may be used as a tool for identifying nucleophilic ligandable hotspots by chemoproteomic approaches. | [reaction suitability]
reaction type: click chemistry
reagent type: cross-linking reagent | [IC 50]
Non-cleavable Linker |
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Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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