| Identification | Back Directory | [Name]
Propargyl-PEG7-alcohol | [CAS]
944560-99-0 | [Synonyms]
Alkyne-PEG6-OH
HC≡C-CH2-PEG6-OH
Propargyl-PEG6-OH
Propyne-PEG6-alcohol
Propargyl-PEG7-alcohol
3,6,9,12,15,18-Hexaoxahenicos-20-yn-1-ol
(2-(2-(2-(2-(2-(2-hydroxyethoxy)-ethoxy)-ethoxy)-ethoxy)-ethoxy)-ethyl) propargyl ether | [Molecular Formula]
C15H28O7 | [MDL Number]
MFCD22574806 | [MOL File]
944560-99-0.mol | [Molecular Weight]
320.38 |
| Chemical Properties | Back Directory | [Boiling point ]
408.8±40.0 °C(Predicted) | [density ]
1.083±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMSO, DCM, DMF | [form ]
Liquid | [pka]
14.36±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
Propargyl-PEG7-alcohol is a propargyl linker that can react with azide compounds or biomolecules via copper catalyzed Click Chemistry. | [Uses]
Propargyl-PEG6-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG6-alcohol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] Goswami LN, et al. Efficient synthesis of diverse heterobifunctionalized clickable oligo(ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery. Org Biomol Chem. 2013 Feb 21;11(7):1116-26. DOI:10.1039/c2ob26968f |
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