| Identification | Back Directory | [Name]
Biotin-PEG3-CH2COOH | [CAS]
1189560-96-0 | [Synonyms]
CAS_1189560-96-0
Biotin-PEG3-CH2COOH
Biotin-PEG3-acetic Acid
11-(Biotinamido)-3,6,9-trioxaundecanoic Acid
13-oxo-17-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9-trioxa-12-azaheptadecanoic acid
3,6,9-Trioxa-12-azaheptadecanoic acid, 17-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-13-oxo-
13-oxo-17-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9-trioxa-12-azaheptadecan-1-oic acid | [Molecular Formula]
C18H31N3O7S | [MDL Number]
MFCD30749255 | [MOL File]
1189560-96-0.mol | [Molecular Weight]
433.52 |
| Hazard Information | Back Directory | [Uses]
Biotin-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [Biological Activity]
Biotin-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | [IC 50]
PEGs | [References]
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
|
| Company Name: |
TCI Europe
|
| Tel: |
320-37350700 |
| Website: |
https://www.tcichemicals.com/de/de/index.html |
|