| Identification | Back Directory | [Name]
BenzaMide, N-[4-chloro-3-(trifluoroMethyl)phenyl]-2-[2-(diMethylaMino)ethoxy]-6-ethoxy- | [CAS]
1311423-89-8 | [Synonyms]
YF-2;YF 2
N-[4-chloro-3-(trifluoromethyl)phenyl]-2-[2-(dimethylamino)ethoxy]-6-ethoxybenzamide
BenzaMide, N-[4-chloro-3-(trifluoroMethyl)phenyl]-2-[2-(diMethylaMino)ethoxy]-6-ethoxy- | [Molecular Formula]
C20H22ClF3N2O3 | [MDL Number]
MFCD22665763 | [MOL File]
1311423-89-8.mol | [Molecular Weight]
430.85 |
| Chemical Properties | Back Directory | [Boiling point ]
460.8±45.0 °C(Predicted) | [density ]
1.285±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml | [form ]
A crystalline solid | [pka]
11.75±0.70(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
YF-2 is an activator of histone acetyltransferase (HAT). | [in vivo]
YF-2 (20 mg/kg, 2 hours befor electric shock or 5 mg/kg, 30 min before the electric shock, i.p.) rescues the defect in contextual memory in mice, and shows no effect on contextual memory alone at 20 mg/kg in mice[1]. | [IC 50]
GCN5/PCAF: 29.04 μM (EC50); GCN5: 49.31 μM (EC50); CBP: 2.75 μM (EC50) | [storage]
Store at -20°C |
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| Company Name: |
SPIRO PHARMA
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| Tel: |
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| Website: |
www.spiropharma.com.cn |
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