| Identification | Back Directory | [Name]
Yhhu-3792 | [CAS]
2097826-24-7 | [Synonyms]
Yhhu-3792
2,4-Quinazolinediamine, 5-(3-methoxyphenoxy)-N2-[4-(1-methylethyl)phenyl]- | [Molecular Formula]
C24H24N4O2 | [MOL File]
2097826-24-7.mol | [Molecular Weight]
400.47 |
| Chemical Properties | Back Directory | [Boiling point ]
608.8±65.0 °C(Predicted) | [density ]
1.239±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
7.81±0.30(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Yhhu-3792 enhances the self-renewal capability of neural stem cells (NSCs). Yhhu-3792 activates Notch signaling pathway and promotes the expression of Hes3 and Hes5. Yhhu-3792 expands the NSCs pool and promotes endogenous neurogenesis in the hippocampal dentate gyrus (DG) in mouse. Yhhu-3792 increases the spatial and episodic memory abilities of mice. Yhhu-3792 has the potential for the research of impairment of learning and memory associated DG dysfunction[1]. | [References]
[1] Lu H, et al. A Novel 2-Phenylamino-Quinazoline-Based Compound Expands the Neural Stem Cell Pool and Promotes the Hippocampal Neurogenesis and the Cognitive Ability of Adult Mice. Stem Cells. 2018 Aug;36(8):1273-1285. DOI:10.1002/stem.2843 |
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| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
www.chemicalbook.com/showsupplierproductslist927327/0_en.htm |
| Company Name: |
Biorbyt Ltd.
|
| Tel: |
+44 (0)1223 859 353 |
| Website: |
http://www.biorbyt.com |
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