| Identification | Back Directory | [Name]
E3 ligase Ligand-Linker Conjugates 37 | [CAS]
1312302-14-9 | [Synonyms]
cIAP1 Ligand-Linker Conjugates 2
E3 ligase Ligand-Linker Conjugates 37 | [Molecular Formula]
C37H48N4O7 | [MDL Number]
MFCD32197267 | [MOL File]
1312302-14-9.mol | [Molecular Weight]
660.8 |
| Hazard Information | Back Directory | [Uses]
cIAP1 Ligand-Linker Conjugates 2 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 2 can be used to design SNIPERs[1]. | [IC 50]
cIAP1 | [References]
[1] Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78. DOI:10.1016/j.bmc.2011.09.041 |
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