| Identification | Back Directory | [Name]
E3 ligase Ligand-Linker Conjugates 36 | [CAS]
1351169-40-8 | [Synonyms]
cIAP1 Ligand-Linker Conjugates 14
E3 ligase Ligand-Linker Conjugates 36
12,15,18-Trioxa-2,6,9-triazaeicosanedioic acid, 4-hydroxy-7-(2-methylpropyl)-5,8-dioxo-3-(phenylmethyl)-, 1-(9H-fluoren-9-ylmethyl) ester, (3R,4S,7S)- | [Molecular Formula]
C39H49N3O10 | [MDL Number]
MFCD32197266 | [MOL File]
1351169-40-8.mol | [Molecular Weight]
719.82 |
| Hazard Information | Back Directory | [Uses]
cIAP1 Ligand-Linker Conjugates 14 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 14 can be used to design SNIPERs[1]. | [IC 50]
cIAP1 | [References]
[1] Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78. DOI:10.1016/j.bmc.2011.09.041 |
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