| Identification | Back Directory | [Name]
Diazo Biotin-PEG3-Azide | [CAS]
1339202-33-3 | [Synonyms]
Azo biotin-azide
Diazo Biotin-Azide
Diazo Biotin-PEG3-Azide
Diazo Biotin-Azide,Diazo Biotin-N3 | [Molecular Formula]
C33H45N9O7S | [MDL Number]
MFCD28334530 | [MOL File]
1339202-33-3.mol | [Molecular Weight]
711.84 |
| Hazard Information | Back Directory | [Description]
Diazo Biotin-PEG3-azide is useful for introducing a biotin moiety to alkyne-containing biomolecules using Cu(I)-catalyzed Click Chemistry. The hydrophilic spacer arm provides better solubility to the labeled molecules in aqueous media. Diazo allows efficient release of captured biotinylated molecules from streptavidin using sodium dithionite (Na2S2O4). | [Uses]
Azo biotin-azide is a linker that contains a biotin moiety connected to an azide group through a spacer arm containing a diazo group that can be cleaved with 50 mM sodium dithionite solution. The biotin can be captured by streptavidin and the azide can react with terminal or strained alkynes. | [reaction suitability]
reaction type: click chemistry | [IC 50]
PEGs |
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| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|