| Identification | Back Directory | [Name]
Biotin-PEG2-NH-Boc | [CAS]
175885-18-4 | [Synonyms]
Biotin-PEG2-NH-Boc
tert-Butyl (2-(2-(2-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethoxy)ethoxy)ethyl)carbamate
5,8-Dioxa-2,11-diazahexadecanoic acid, 16-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-12-oxo-, 1,1-dimethylethyl ester | [Molecular Formula]
C21H38N4O6S | [MDL Number]
MFCD30527392 | [MOL File]
175885-18-4.mol | [Molecular Weight]
474.61 |
| Hazard Information | Back Directory | [Description]
Biotin-PEG2-NH-Boc is a PEG linker with biotin and Boc protected amine moieties. The biotin group is used for the conjugation of proteins and can also be used for labeling. Boc can be removed under acidic condition. | [Uses]
Biotin-PEG2-NH-Boc is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329 |
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