| | Identification | Back Directory |  | [Name] 
 15-[D(+)-BIOTINYLAMINO]-4,7,10,13-TETRAOXAPENTADECANOIC ACID
 |  | [CAS] 
 721431-18-1
 |  | [Synonyms] 
 otin-PEG4-Acid
 Biotin-PEG4-COOH
 Biotin-PEG5-Acid
 Biotin-PEG4-Acid
 Biotin-PEG24-Acid
 dPEG??-biotin acid
 (+)-Biotin-PEG4-acid
 Biotin-PEGn-Acid (n=4,24)
 Biotin-PEG4-propionic acid
 (+)-Biotin-PEG4-CH2CH2COOH
 (+)-Biotin-PEG24-CH2CH2COOH
 (+)-BIOTIN-PEG4-PROPIONIC ACID
 3-Amino(peg4)propionic acid biotinamide
 (+)-Biotin-PEG4-propionic acid
 15-(Biotinamido)-4,7,10,13-tetraoxapentadecanoic Acid
 15-[D(+)-BIOTINYLAMINO]-4,7,10,13-TETRAOXAPENTADECANOIC ACID
 21-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-17-oxo-4,7,10,13-tetraoxa-16-azaheneicosanoic acid
 4,7,10,13-Tetraoxa-16-azaheneicosanoicacid, 21-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-17-oxo-
 |  | [Molecular Formula] 
 C21H37N3O8S
 |  | [MDL Number] 
 MFCD08457831
 |  | [MOL File] 
 721431-18-1.mol
 |  | [Molecular Weight] 
 491.6
 | 
 | Chemical Properties | Back Directory |  | [Boiling point ] 
 784.8±60.0 °C(Predicted)
 |  | [density ] 
 1.211±0.06 g/cm3(Predicted)
 |  | [storage temp. ] 
 Sealed in dry,2-8°C
 |  | [solubility ] 
 Soluble in Water, DMSO, DMF
 |  | [form ] 
 Solid
 |  | [pka] 
 4.28±0.10(Predicted)
 |  | [color ] 
 White to off-white
 |  | [Appearance] 
 white to beige powder
 | 
 | Hazard Information | Back Directory |  | [Description] 
 Biotin-PEG4-acid is a biotinylation reagent which can react with amine molecules in the presence of activator EDC or HATU.  PEG attached to the biotin gives an extended spacer arm that permits the biotin to reach into the binding pocket of the protein. The PEG moiety also increases solubility of Biotin-PEG conjugates considerably.
 |  | [Chemical Properties] 
 White powder
 |  | [Uses] 
 Biotin-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
 |  | [IC 50] 
 PEGs
 | 
 |  |